Are Newer Antiepileptic Drugs Associated with Improved Safety in Pregnancy Compared to Older Antiepileptic Drugs?
نویسندگان
چکیده
منابع مشابه
Are newer antiepileptic drugs associated with improved safety in pregnancy compared to older antiepileptic drugs?
Commentary As a group, antiepileptic drugs (AEDs) are associated with an increased risk of major congenital malformations (MCMs) (1). Older AEDs are the best studied. Valproate (VPA) is consistently associated with an increased risk of MCMs including an increased risk of spina bifida (2). Phenobarbital (PB) exposure increases the risk of MCMs, including oral clefts (3). Although not consistent ...
متن کاملNewer antiepileptic drugs
Epilepsy is a very common neurological disorder with high prevalence and incidence. Several conventional antiepileptic drugs are being used for the treatment of various types of epilepsies. Over the last two decades, there has been a rapid expansion in the number and types of available antiepileptic drugs (AED). Newer AEDs are now available for the treatment of various forms of epilepsies. Lamo...
متن کاملComparative safety of antiepileptic drugs during pregnancy.
OBJECTIVE To assess the safety of the newer antiepileptic drugs (AEDs) during pregnancy. METHODS The study population was pregnant women who enrolled in the North American AED Pregnancy Registry between 1997 and 2011. Data on AED use and maternal characteristics were collected through phone interviews at enrollment, at 7 months' gestation, and postpartum. Malformations were confirmed by medic...
متن کاملAntiepileptic Drugs
Antiepileptics are a very important class of medications, and the number of these drugs available for clinical use has increased dramatically in the last decade. The pharmacology and indications for use in a variety of physiatric patient groups are comprehensively and systematically reviewed.
متن کاملAntiepileptic Drugs
GENERIC NAME PAGE Carbamazepine 378 Clobazam 381 Clonazepam 380 Clorazepate 381 Diazepam 383 Ethosuximide 381 Ethotoin 378 Felbamate 382 Fosphenytoin 383 Gabapentin 382 Levetiracetam 382 Lamotrigine 379 Lorazepam 380 GENERIC NAME PAGE Mephenytoin 378 Mephobarbital 381 Metharbital 381 Nitrazepam 381 Oxcarbazepine 379 Phenobarbital 381 Phenytoin 377 Primidone 381 Tiagabine 381 Topiramate 379 Valp...
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ژورنال
عنوان ژورنال: Epilepsy Currents
سال: 2013
ISSN: 1535-7597,1535-7511
DOI: 10.5698/1535-7511-13.1.15